Examples: chr1:2-33837011; CD1C; L1HS; K562

What is L1MethDB ?

L1MethDB provides a comprehensive resource and web interface to explore the genomic location and the DNA methylation status of human full-length LINE-1 elements (L1) at single-locus, single-molecule and single-nucleotide resolutions obtained from bs-ATLAS-seq experiments.
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Bs-ATLAS-seq provides both the location of L1 insertions and their methylation state. Cell lines included in L1MethDB are described below:
Table 1 – Panel of cell lines included in the database.
Name Description Sex
Normal primary fibroblast
BJ Foreskin fibroblasts
IMR-90 Embryonic lung fibroblasts
MRC-5 Embryonic lung fibroblasts
Human embryonic stem cell
H1 Embryonic stem cells
Experimentally immortalized and transformed cells
HEK-293 Adenovirus-immortalized embryonal kidney cells
HEK-293T A derivative of HEK-293 further transformed by SV40 Large T antigen
Cancer cells
HepG2 Hepatoblastoma cells
K-562 Chronic myelogenous leukemia cells
MCF-7 Breast adenocarcinoma cells
HeLa-S3 Cervical cancer cells
HCT-116 Colon cancer cells
2102Ep Embryonal carcinoma cells
12

CELL LINES

8

L1 FAMILIES

5426

L1 LOCI